Lipid Biology for Prediction and Prevention of Psychotic Disorders and Persistent Depression in Young People

Effects of 6-months of SSRI use on DNA-methylation and gene expression in blood

LF Barker, AF McRae, HP Yuen, AK Henders, LM Wallace, T Lin, E Davyson, C Phassouliotis, J Spark, M Kerr, R Street, EM Byrne, GP Amminger, B Nelson, NR Wray, PD McGorry

2026-07-01

Background Selective serotonin reuptake inhibitors (SSRIs) are a recommended first line medication for the treatment of major depr..

Characterizing the Clinical Trajectory and Predicting Persistence and Deterioration of Attenuated Psychotic Symptoms in Ultra-High-Risk Individuals

C Wannan, I Scott, D Dwyer, SR Clark, S Hartmann, RR Ye, GP Amminger, HP Yuen, S Lavoie, C Markulev, MR Schaefer, JA Hartmann, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, G Berger, EYH Chen, L De Haan, DH Nieman

2025-11-01

Background Almost 40% of individuals at ultra-high risk (UHR) for psychosis experience persistent attenuated psychotic symptoms (A..

Therapy process factors in early psychosis: The effect of working alliance on clinical symptoms and cognitive biases in Ultra High Risk young people

P Bagrowska, C Wannan, A Polari, HP Yuen, P Amminger, M Kerr, J Spark, N Wallis, M Shumway, C Carter, L Dixon, TA Niendam, R Loewy, P McGorry, B Nelson

2025-10-01

Approximately 25 % of individuals at Ultra High Risk (UHR) transition to a full psychotic disorder. Cognitive biases are thought t..

White Blood Cell Proportions Are Associated With Response to Psychosocial Therapy in Young People at Ultra-High Risk for Psychosis

LF Barker, AF McRae, HP Yuen, AK Henders, LM Wallace, T Lin, C Phassouliotis, J Spark, M Kerr, EM Byrne, GP Amminger, B Nelson, NR Wray, PD McGorry

2025-09-01

Background: White blood cell (WBC) counts, DNA methylation, and gene expression are reported to be associated with psychosis. Howe..

Transdiagnostic Symptom Dimensions in Individuals at Ultra-High Risk for Psychosis: Towards Dimensional Representations of Pluripotent Risk

JCC Schulte-Strathaus, C Rauschenberg, I Paetzold, D Quattrone, J Hartmann, P Amminger, HP Yuen, PD McGorry, B Nelson, U Reininghaus

2025-08-01

Intro: Research has shifted focus from categorical to dimensional conceptualisations of mental health conditions. This is supporte..

Association between non-adherence to fish oil or placebo as a risk factor of transition to psychosis in ultra-high-risk individuals in the NEURAPRO study

M Schlögelhofer, A Lin, C Markulev, MR Schäfer, PD McGorry, B Nelson, R Street, N Mossaheb, S Smesny, IB Hickie, G Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson, AR Yung, GP Amminger

2025-01-01

Objective: Non-adherence is an important factor in clinical trials, which has not been investigated in people at ultra-high risk (..

Development and temporal validation of a clinical prediction model of transition to psychosis in individuals at ultra-high risk in the UHR 1000 cohort

S Hartmann, D Dwyer, B Cavve, EM Byrne, I Scott, C Gao, C Wannan, HP Yuen, J Hartmann, A Lin, SJ Wood, JTW Wigman, CM Middeldorp, A Thompson, P Amminger, M Schlögelhofer, A Riecher-Rössler, EYH Chen, IB Hickie, LJ Phillips

2024-10-01

The concept of ultra-high risk for psychosis (UHR) has been at the forefront of psychiatric research for several decades, with the..

Erythrocyte membrane fatty acid concentrations and myelin integrity in young people at ultra-high risk of psychosis

M Collins, C Bartholomeusz, C Mei, M Kerr, J Spark, N Wallis, A Polari, S Baird, K Buccilli, SJA Dempsey, N Ferguson, M Formica, M Krcmar, AL Quinn, C Wannan, S Oldham, A Fornito, Y Mebrahtu, A Ruslins, R Street

2024-07-01

Decreased white matter (WM) integrity and disturbance in fatty acid composition have been reported in individuals at ultra-high ri..

Combining Clinical With Cognitive or Magnetic Resonance Imaging Data for Predicting Transition to Psychosis in Ultra High-Risk Patients: Data From the PACE 400 Cohort

Simon Hartmann, Micah Cearns, Christos Pantelis, Dominic Dwyer, Blake Cavve, Enda Byrne, Isabelle Scott, Hok Pan Yuen, Caroline Gao, Kelly Allott, Ashleigh Lin, Stephen J Wood, Johanna TW Wigman, G Paul Amminger, Patrick D McGorry, Alison R Yung, Barnaby Nelson, Scott R Clark

2024-04-01

Background: Multimodal modeling that combines biological and clinical data shows promise in predicting transition to psychosis in ..

The Addition of Fish Oil to Cognitive Behavioral Case Management for Youth Depression: A Randomized, Double-Blind, Placebo-Controlled, Multicenter Clinical Trial

GP Amminger, S Rice, CG Davey, AL Quinn, DF Hermens, N Zmicerevska, A Nichles, I Hickie, L Incerti, A Weller, S Joseph, Z Hilton, C Pugh, M Rayner, N Reid, A Ratheesh, AR Yung, HP Yuen, A Mackinnon, S Hetrick

2024-03-01

Background: Clinical trials suggest that long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs) (fish oil) may reduce depressi..

A Sequential Adaptive Intervention Strategy Targeting Remission and Functional Recovery in Young People at Ultrahigh Risk of Psychosis: The Staged Treatment in Early Psychosis (STEP) Sequential Multiple Assignment Randomized Trial

PD Mcgorry, C Mei, GP Amminger, HP Yuen, M Kerr, J Spark, N Wallis, A Polari, S Baird, K Buccilli, SJA Dempsey, N Ferguson, M Formica, M Krcmar, AL Quinn, Y Mebrahtu, A Ruslins, R Street, C Wannan, L Dixon

2023-09-06

Importance: Clinical trials have not established the optimal type, sequence, and duration of interventions for people at ultrahigh..

Evidence that complement and coagulation proteins are mediating the clinical response to omega-3 fatty acids: A mass spectrometry-based investigation in subjects at clinical high-risk for psychosis

SR Susai, C Healy, D Mongan, M Heurich, JF Byrne, M Cannon, G Cagney, K Wynne, C Markulev, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft

2022-12-01

Preliminary evidence indicates beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) in early psychosis. The present s..

Effects of omega-3 polyunsaturated fatty acid supplementation on cognitive functioning in youth at ultra-high risk for psychosis: secondary analysis of the NEURAPRO randomised controlled trial

N Cheng, A Mclaverty, B Nelson, C Markulev, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, R Street, A Thompson, HP Yuen

2022-09-08

Background Cognitive impairments are well-established features of psychotic disorders and are present when individuals are at ultr..

Cannabidiol for Treatment-Resistant Anxiety Disorders in Young People: An Open-Label Trial

M Berger, E Li, S Rice, CG Davey, A Ratheesh, S Adams, H Jackson, S Hetrick, A Parker, T Spelman, R Kevin, IS McGregor, P McGorry, GP Amminger

2022-09-01

Background: Treatment resistance is a significant problem among young people experiencing moderate-to-severe anxiety, affecting ne..

Has improved treatment contributed to the declining rate of transition to psychosis in ultra-high-risk cohorts?

MJC Formica, LJ Phillips, JA Hartmann, AR Yung, SJ Wood, A Lin, GP Amminger, PD McGorry, B Nelson

2022-05-01

Background: The factors contributing to declining psychotic disorder transition rates in ultra-high-risk populations remain unclea..

The association of plasma inflammatory markers with omega-3 fatty acids and their mediating role in psychotic symptoms and functioning: An analysis of the NEURAPRO clinical trial

SR Susai, D Mongan, C Healy, M Cannon, B Nelson, C Markulev, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson

2022-01-01

Background: There is increasing evidence that dysregulation of polyunsaturated fatty acids (FAs) mediated membrane function plays ..

Twelve-Month Cognitive Trajectories in Individuals at Ultra-High Risk for Psychosis: A Latent Class Analysis

K Allott, SJ Schmidt, HP Yuen, SJ Wood, B Nelson, C Markulev, S Lavoie, WJ Brewer, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma

2022-01-01

Understanding longitudinal cognitive performance in individuals at ultra-high risk for psychosis (UHR) is important for informing ..

Greater preference for eveningness is associated with negative symptoms in an ultra-high risk for psychosis sample

JJ Shetty, C Nicholas, B Nelson, PD McGorry, S Lavoie, C Markulev, MR Schäfer, A Thompson, HP Yuen, AR Yung, DH Nieman, L de Haan, GP Amminger, JA Hartmann

2021-12-01

Aim: Investigating biological processes in at-risk individuals may help elucidate the aetiological mechanisms underlying psychosis..

Characterization and prediction of clinical pathways of vulnerability to psychosis through graph signal processing

C Sandini, D Zöller, M Schneider, A Tarun, M Armondo, B Nelson, PG Amminger, HP Yuen, C Markulev, MR Schäffer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EY Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler

2021-09-01

There is a growing recognition that psychiatric symptoms have the potential to causally interact with one another. Particularly in..

Association of Structural Magnetic Resonance Imaging Measures with Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

M Jalbrzikowski, RA Hayes, SJ Wood, D Nordholm, JH Zhou, P Fusar-Poli, PJ Uhlhaas, T Takahashi, G Sugranyes, YB Kwak, DH Mathalon, N Katagiri, CI Hooker, L Smigielski, T Colibazzi, E Via, J Tang, S Koike, PE Rasser, C Michel

2021-07-01

Importance: The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled neuroimaging sample of individuals at..

Toxoplasma gondii, Herpesviridae and long-term risk of transition to first-episode psychosis in an ultra high-risk sample

E Burkhardt, M Berger, RH Yolken, A Lin, HP Yuen, SJ Wood, SM Francey, A Thompson, PD McGorry, B Nelson, AR Yung, GP Amminger

2021-07-01

Background: Ultra high-risk (UHR) criteria were introduced to identify people at imminent risk of developing psychosis. To improve..

Comparison of erythrocyte omega-3 index, fatty acids and molecular phospholipid species in people at ultra-high risk of developing psychosis and healthy people

A Alqarni, TW Mitchell, PD McGorry, B Nelson, C Markulev, HP Yuen, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson

2020-12-01

People classified as ultra-high risk (UHR) of developing psychosis have reduced cellular membrane omega-3 and omega-6 polyunsatura..

Supplementation with the omega-3 long chain polyunsaturated fatty acids: Changes in the concentrations of omega-3 index, fatty acids and molecular phospholipids of people at ultra high risk of developing psychosis

A Alqarni, TW Mitchell, PD McGorry, B Nelson, C Markulev, HP Yuen, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson

2020-12-01

Omega-3 long chain polyunsaturated fatty acids (n-3 LCPUFA) are necessary for optimum mental health, with recent studies showing l..

Do schizotypal or borderline personality disorders predict onset of psychotic disorder or persistent attenuated psychotic symptoms in patients at high clinical risk?

H Hadar, H Zhang, LJ Phillips, GP Amminger, GE Berger, EYH Chen, L de Haan, JA Hartmann, IB Hickie, S Lavoie, C Markulev, PD McGorry, N Mossaheb, DH Nieman, M Nordentoft, A Riecher-Rössler, MR Schäfer, M Schlögelhofer, S Smesny, A Thompson

2020-06-01

Novel Modalities for Assessment and Intervention in Youth Mental Health: Digital Interventions and Omega-3 Fatty Acids

Mario Alvarez-Jimenez, G Paul Amminger, Maximus Berger, John Gleeson, Andrew M Chanen

2020-04-28

Experts discuss the potential of early intervention to transform outcomes for people with mental disorders. Mental illness represe..

Cognitive functioning in ultra-high risk for psychosis individuals with and without depression: Secondary analysis of findings from the NEURAPRO randomized clinical trial

SR Mallawaarachchi, GP Amminger, J Farhall, LK Bolt, B Nelson, HP Yuen, PD McGorry, C Markulev, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma

2020-04-01

Neurocognitive impairments are well established in both ultra-high risk (UHR) for psychosis and major depressive disorder (MDD). D..

Basic symptoms in young people at ultra-high risk of psychosis: Association with clinical characteristics and outcomes

S Youn, LJ Phillips, GP Amminger, G Berger, EYH Chen, L de Haan, JA Hartmann, IB Hickie, S Lavoie, C Markulev, PD McGorry, N Mossaheb, DH Nieman, M Nordentoft, A Riecher-Rössler, MR Schäfer, M Schlögelhofer, S Smesny, A Thompson, S Verma

2020-02-01

There has been limited research into the predictive value of basic symptoms and their relationship with other psychopathology in p..

The NEURAPRO Biomarker Analysis: Long-Chain Omega-3 Fatty Acids Improve 6-Month and 12-Month Outcomes in Youths at Ultra-High Risk for Psychosis

GP Amminger, B Nelson, C Markulev, HP Yuen, MR Schäfer, M Berger, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson, AR Yung, PD McGorry

2020-02-01

Background: NEURAPRO was a multicenter, placebo-controlled trial of long-chain omega-3 polyunsaturated fatty acids (n-3 PUFAs) (fi..

The prognostic significance of attenuated psychotic symptoms in help-seeking youth

H Hazan, T Spelman, GP Amminger, I Hickie, PD McGorry, LJ Phillips, R Purcell, SJ Wood, AR Yung, B Nelson

2020-01-01

Background: Recent findings suggest that attenuated psychotic symptoms (APS) might serve as a risk factor for general mental healt..

Trajectories of symptom severity and functioning over a three-year period in a psychosis high-risk sample: A secondary analysis of the Neurapro trial

JA Hartmann, SJ Schmidt, PD McGorry, M Berger, GE Berger, EYH Chen, L de Haan, IB Hickie, S Lavoie, C Markulev, N Mossaheb, DH Nieman, M Nordentoft, A Polari, A Riecher-Rössler, MR Schäfer, M Schlögelhofer, S Smesny, A Thompson, SK Verma

2020-01-01

The Ultra-High Risk (UHR) for psychosis group is known to be heterogeneous with diverse outcomes. This study aimed to: 1. Identify..

The addition of fluoxetine to cognitive behavioural therapy for youth depression (YoDA-C): a randomised, double-blind, placebo-controlled, multicentre clinical trial

CG Davey, AM Chanen, SE Hetrick, SM Cotton, A Ratheesh, GP Amminger, J Koutsogiannis, M Phelan, E Mullen, BJ Harrison, S Rice, AG Parker, OM Dean, A Weller, M Kerr, AL Quinn, L Catania, N Kazantzis, PD McGorry, M Berk

2019-09-01

Background: Medication is commonly used to treat youth depression, but whether medication should be added to cognitive behavioural..

Broad clinical high-risk mental state (CHARMS): Methodology of a cohort study validating criteria for pluripotent risk

JA Hartmann, B Nelson, R Spooner, G Paul Amminger, A Chanen, CG Davey, M McHugh, A Ratheesh, D Treen, HP Yuen, PD McGorry

2019-06-01

Aim: The development of the ultra-high risk (UHR) criteria for psychosis created a new paradigm for the prevention research in psy..

Neurocognition as a predictor of transition to psychotic disorder and functional outcomes in ultra-high risk participants: Findings from the NEURAPRO randomized clinical trial

LK Bolt, GP Amminger, J Farhall, PD McGorry, B Nelson, C Markulev, HP Yuen, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L de Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson

2019-04-01

Background: Neurocognitive impairments experienced by individuals at ultra-high risk (UHR) for psychosis are potential predictors ..

The relationship between childhood trauma and clinical characteristics in ultra-high risk for psychosis youth

C de Vos, A Thompson, P Amminger, S Bendall, L de Haan, J Hartmann, S Lavoie, C Markulev, P McGorry, D Nieman, L Phillips, U Reininghaus, HP Yuen, A Yung, B Nelson

2019-01-02

Mounting evidence suggests that a history of childhood trauma (CT) is associated with an increased risk of developing a psychotic ..

Chapter 9 – Novel Treatment Strategies: Biological

G Paul Amminger, Maximus Berger

2019-01-01

NEURAPRO: A multi-centre RCT of omega-3 polyunsaturated fatty acids versus placebo in young people at ultra-high risk of psychotic disorders - Medium-term follow-up and clinical course

B Nelson, GP Amminger, HP Yuen, C Markulev, S Lavoie, MR Schäfer, JA Hartmann, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, G Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson, AR Yung

2018-12-01

This study reports a medium-term follow-up of a randomised, double-blind, placebo-controlled trial of omega-3 polyunsaturated fatt..

Recent meta-analyses in the clinical high risk for psychosis population: Clinical interpretation of findings and suggestions for future research

B Nelson, GP Amminger, PD McGorry

2018-10-12

One of the major advances over the past 20 years in psychiatry is the capacity not only to identify people at incipient risk for p..

In vivo imaging of oxidative stress and fronto-limbic white matter integrity in young adults with mood disorders

DF Hermens, SN Hatton, RSC Lee, SL Naismith, SL Duffy, G Paul Amminger, M Kaur, EM Scott, J Lagopoulos, IB Hickie

2018-03-01

Fronto-limbic connectivity is compromised in mood disorders, as reflected by impairments in white matter (WM) integrity revealed b..

Predictors of longer-term outcome in the Vienna omega-3 high-risk study

N Mossaheb, MR Schäfer, M Schlögelhofer, CM Klier, S Smesny, PD McGorry, M Berger, GP Amminger

2018-03-01

Longer-term data on ω-3 polyunsaturated fatty acids (PUFA) for prevention of psychosis in (ultra high risk) UHR individuals have i..

Opening the Black Box of Cognitive-Behavioural Case Management in Clients with Ultra-High Risk for Psychosis

JA Hartmann, PD McGorry, SJ Schmidt, GP Amminger, HP Yuen, C Markulev, GE Berger, EYH Chen, L De Haan, IB Hickie, S Lavoie, MJ McHugh, N Mossaheb, DH Nieman, M Nordentoft, A Riecher-Rössler, MR Schäfer, M Schlögelhofer, S Smesny, A Thompson

2017-10-01

Background: Cognitive-behavioural therapy (CBT) is the first-choice treatment in clients with ultra-high risk (UHR) for psychosis...

Negative psychosis prevention trials

PD McGorry, B Nelson, P Amminger

2017-06-01

Novel biotherapies are needed in youth mental health

G Paul Amminger, M Berger, SM Rice, CG Davey, MR Schäfer, PD McGorry

2017-04-01

Adverse effects and lack of efficacy in a significant number of patients limit pharmaceutical interventions in youth psychiatry. T..

Effect of ω-3 polyunsaturated fatty acids in young people at ultrahigh risk for psychotic disorders: The NEURAPRO randomized clinical trial

PD McGorry, B Nelson, C Markulev, HP Yuen, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma, A Thompson, AR Yung, G Paul Amminger

2017-01-01

IMPORTANCE :A promising treatment to prevent onset and improve outcomes in patients at ultrahigh risk for psychosis is dietary sup..

Erythrocyte glutathione levels as long-term predictor of transition to psychosis

S Lavoie, M Berger, M Schlögelhofer, MR Schäfer, S Rice, SW Kim, J Hesse, PD McGorry, S Smesny, GP Amminger

2017-01-01

A high proportion of individuals deemed at elevated risk for psychosis will actually never progress to develop the illness. Pharma..

Omega-6 to omega-3 polyunsaturated fatty acid ratio and subsequent mood disorders in young people with at-risk mental states: A 7-year longitudinal study

ME Berger, S Smesny, SW Kim, CG Davey, S Rice, Z Sarnyai, M Schlögelhofer, MR Schäfer, M Berk, PD McGorry, GP Amminger

2017-01-01

While cross-sectional studies suggest that patients with mood disorders have a higher ratio of omega-6 to omega-3 polyunsaturated ..

Differential expression of the inflammation marker IL12p40 in the at-risk mental state for psychosis: A predictor of transition to psychotic disorder?

M Föcking, P Dicker, LM Lopez, M Cannon, MR Schäfer, PD McGorry, S Smesny, DR Cotter, GP Amminger

2016-09-20

Background: The identification of biomarkers of transition from the at-risk mental state (ARMS) to psychotic disorder is important..

Cortisol awakening response in patients with psychosis: Systematic review and meta-analysis

M Berger, AK Kraeuter, D Romanik, P Malouf, GP Amminger, Z Sarnyai

2016-09-01

The cortisol awakening response (CAR), defined as the increase in cortisol release in response to waking up, shows associations wi..

White matter integrity in individuals at ultra-high risk for psychosis: A systematic review and discussion of the role of polyunsaturated fatty acids

N Vijayakumar, C Bartholomeusz, T Whitford, DF Hermens, B Nelson, S Rice, S Whittle, C Pantelis, P McGorry, MR Schäfer, GP Amminger

2016-08-11

Background: Schizophrenia is thought to be a neurodevelopmental disorder with pathophysiological processes beginning in the brain ..

Relationship between erythrocyte fatty acid composition and psychopathology in the Vienna omega-3 study

SW Kim, M Jhon, JM Kim, S Smesny, S Rice, M Berk, CM Klier, PD McGorry, MR Schäfer, GP Amminger

2016-03-01

This study investigated the relationship between erythrocyte membrane fatty acid (FA) levels and the severity of symptoms of indiv..

Associations of hippocampal metabolism and regional brain grey matter in neuroleptic-naïve ultra-high-risk subjects and first-episode schizophrenia

I Nenadic, R Maitra, S Basu, M Dietzek, N Schönfeld, C Lorenz, A Gussew, GP Amminger, P McGorry, JR Reichenbach, H Sauer, C Gaser, S Smesny

2015-10-01

Hippocampal pathology has been shown to be central to the pathophysiology of schizophrenia and a putative risk marker for developi..

Longer-term outcome in the prevention of psychotic disorders by the Vienna omega-3 study

GP Amminger, MR Schäfer, M Schlögelhofer, CM Klier, PD McGorry

2015-08-11

Long-chain omega-3 polyunsaturated fatty acids (PUFAs) are essential for neural development and function. As key components of bra..

Erythrocyte polyunsaturated fatty acid levels in young people at ultra-high risk for psychotic disorder and healthy adolescent controls

SM Rice, MR Schäfer, C Klier, N Mossaheb, N Vijayakumar, GP Amminger

2015-07-30

Erythrocyte polyunsaturated fatty acid (PUFA) levels from individuals at ultra-high risk (UHR) for psychosis (n=80) were compared ..

Predictors of treatment response in young people at ultra-high risk for psychosis who received long-chain omega-3 fatty acids

GP Amminger, A Mechelli, S Rice, SW Kim, CM Klier, RK McNamara, M Berk, PD McGorry, MR Schäfer

2015-01-01

Previous efforts in the prospective evaluation of individuals who experience attenuated psychotic symptoms have attempted to isola..